PQQ is considered a novel cofactor with antioxidant and B vitamin-like activity, it enhances the biosynthesis of nerve growth factor (NGF), a key protein involved in the growth and survival of neurons*. PQQ and CoQ10 work together to promote antioxidant activity and mitochondrial health, providing multifunctional support for cardiovascular health and neuroprotection.* BioPQQ® is manufactured in Japan using a patented natural fermentation process. Natural Factors CoQ10 is naturally fermented, consisting only of the natural trans isomer identical to the body’s own CoQ10.